Contacting Expedia Headquarters. Expedia is a travel website, but it is also the company behind websites like Hotwire.com and CarRentals.com. You can plan every aspect of your trip with the help of Expedia websites. If in case you booked a tour through a travel agency, the itinerary should come from the travel agency. If your vacation is a combination of a tour with a travel agency and DIY, then come…